Responding extremely well to 2nd gen ADT has extended my life. but I have paid a price.
It's getting harder.
I was 42 years old when I was diagnosed, so I was still in that age group where I was really active. The first side effects, of ADT was fatigue. That could have been the death nail for me if not for my caregiver, true love, my Wife. Mandy was dogmatic at keeping me active. She saved my life. Staying active, reduced the fatigue and the hot flashes and helped me to maintain mental sharpness. It combatted depression. I didn't enjoy it and I didn't want to do it but after a while when my body had adjusted to its new chemical make up , and while i had been working through it by being active, I was able to fight back most of the side effects. I stayed active while adjusting to a new normal. There was no way I was ever going to recover libido, but we work through that as well. 17 years down the road, we are still in love and working through that as well.
The newer second gen drugs work better at blocking/stopping Testosterone production. in my case, the drug that I am taking works by blocking residual testosterone production in the adrenals. That would be fine if it was only blocking the testosterones, but what abiraterone acetate does is shut down the adrenal system. This is why patients on Abiraterone acetate have to supplement the steroids their body no longer produces. Like I said, it's a trade-off. The side effects just got worse. It would be fine if I was still in my 40s or even in my early 50s. I am not. When first I started this medication. I was younger. It was easier. Now I am aging and I'm still trying to maintain physical activity but it's getting harder. Mandy rides her bicycle alone probably half the time. If I ride my bike now it's hard to ride it again for a few days. The last hike we went on together was on a paved trail on Mount Rainier. I no longer go to work every day. It's probably a good thing because I need naps. I can't work in the yard like I used to. The only way I am able to get anything done is because when we bought our home, we bought one of those miniature Kabota tractors. It has been a lifesaver. I can mow the lawn with it and it has a loader bucket, so I'm able to do the necessary jobs that go along with homeownership. It's getting harder .
The sun came out last week. I was able to go outside. I felt better. It's hardest in the winter time. I used to go to work and although when I was there, I slept in my chair, a lot, at least in the winter time I was able to be a little active. Now I am just home. I have nowhere to go. I have nothing to do it's cold and it's wet or it's cold and it's snowy or the sky is blue but it's still bitter cold outside. I think staying active is what helps most with the other side effect of androgen deprivation therapy, depression!. We are vitamin D, deficient here in Southwest Washington.. The winter blues are very real here. It's worse on androgen deprivation therapy. Winters are hardest, even when I supplement vitamin D.
It's hard, but I have people. I have people who raise my spirits. They cheer me up simply by a phone call or stopping by for a cuppa coffee with a little whiskey, mixed in for flavor. I have my wife who has been there since day one and has never ever stopped being my cheerleader, and a well of encouragement. Sometimes even a swift kick in the ass. Where would I be without her? Where would I be without them my brothers, my friends my family my wife continue to be there for me. They continue to give me a reason to live. They continue to encourage me to live my life every day . Where would I be if they were not in my life? I don't think I would be here. Kindest regards, Todd
